Nobody today can reliably estimating what global migration and entering a post-fossil energy generation will mean for urban design and architecture in the future. Yet as Michel Serres suggests, research has a key role to play in exploring and testing the feasible ways that it might take us on. We conduct a theory-driven and empirically informed, comparative research on global forms of architecture and urbanization, in order to develop new conceptual and theoretical approaches. Methodologically our research unfolds at the intersection of architecture, ethnography, and science and technology studies. Empirical and conceptual accounts of architecture are tightly interwoven, since we are convinced that both is mutually enlightening each other. To search for new insights in the field of architectural theory, with the underlying goal of deploying sustainability, means to reflect both the real complexity of the contemporary city and the concepts that are currently available to improve it. In our research, we are interested in and focused on the “wicked problems” (Rittel/Webber: 1973) of urban design and architecture. In our current research activities we are concerned with two broad problem areas, “urban climates” and “relocation,” with great significance for contemporary societies all over the world.